Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia
Rocca CJ, Goodman SM, Dulin JN, Haquang JH, Gertsman I, Blondelle J, Smith JLM, Heyser CJ, Cherqui S.
Sci. Transl. Med. 2017 Oct 25;9(413)
A general method to fine-tune fluorophores for live-cell and in vivo imaging
Grimm JB, Muthusamy AK, Liang Y, Brown TA, Lemon WC, Patel R, Lu R, Macklin JJ, Keller PJ, Ji N, Lavis LD.
Nat Methods. 2017 Oct;14(10):987-994
Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics
Jeong JW, McCall JG, Shin G, Zhang Y, Al-Hasani R, Kim M, Li S, Sim JY, Jang KI, Shi Y, Hong DY, Liu Y, Schmitz GP, Xia L, He Z, Gamble P, Ray WZ, Huang Y, Bruchas MR, Rogers JA.
Cell. 2015 Jul 30;162(3):662-74
Neural circuits. Labeling of active neural circuits in vivo with designed calcium integrators
Fosque BF, Sun Y, Dana H, Yang CT, Ohyama T, Tadross MR, Patel R, Zlatic M, Kim DS, Ahrens MB, Jayaraman V, Looger LL, Schreiter ER.
Science. 2015 Feb 13;347(6223):755-60
Submission for 10th anniversary issue of Nature Chemical Biology
See journal covers page for the entry that was chosen.
A comparative encyclopedia of DNA elements in the mouse genome
Yue, F. et al Nature. 2014 Nov 20;515(7527):355-64.
Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission
Yan Y, Peng C, Arvin MC, Jin XT, Kim VJ, Ramsey MD, Wang Y, Banala S, Wokosin DL, McIntosh JM, Lavis LD, Drenan RM.
Cell Rep. 2018 May 22;23(8):2236-2244.
Photoactivatable drugs for nicotinic optopharmacology
Banala S, Arvin MC, Bannon NM, Jin XT, Macklin JJ, Wang Y, Peng C, Zhao G, Marshall JJ, Gee KR, Wokosin DL, Kim VJ, McIntosh JM, Contractor A, Lester HA, Kozorovitskiy Y, Drenan RM, Lavis LD.
Nat Methods. 2018 May;15(5):347-350
Reversible Mn2+/Mn4+ double redox in lithium-excess cathode materials
Lee J, Kitchaev DA, Kwon DH, Lee CW, Papp JK, Liu YS, Lun Z, Clément RJ, Shi T, McCloskey BD, Guo J, Balasubramanian M, Ceder G.
Nature. 2018 Apr;556(7700):185-190.
Membrane association of monotopic phosphoglycosyl transferase underpins function
Ray LC, Das D, Entova S, Lukose V, Lynch AJ, Imperiali B, Allen KN.
Nat Chem Biol. 2018 May 16
Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects
Yore MM1, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, Kahn BB.
Cell 2014 Oct 9;159(2):318-32. doi: 10.1016/j.cell.2014.09.035.
Paneth Cell Multipotency Induced by Notch Activation following Injury
Yu S, Tong K, Zhao Y, Balasubramanian I, Yap GS, Ferraris RP, Bonder EM, Verzi MP, Gao N.
Cell Stem Cell 2018 May 23.
TOC Graphics
Dietary Fructose and Microbiota-Derived Short-Chain Fatty Acids Promote Bacteriophage Production in the Gut Symbiont Lactobacillus reuteri
Jee-Hwan Oh, Laura M. Alexander, Meichen Pan, Alan D. Attie, Jens Walter, Jan-Peter van Pijkeren
Published: January 15, 2019
Tolerance of base pair size and shape in postlesion DNA synthesis
Gahlon HL, Schweizer WB, Sturla SJ.
J Am Chem Soc. 2013 May 1;135(17):6384-7
The Postsynthetic Renaissance in Porous Solids
J Am Chem Soc. 2017 Mar 1;139(8):2855-2863. doi: 10.1021/jacs.6b11259.
The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8
Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR.
J Am Chem Soc. 2017 Jun 14;139(23):7872-7885. doi: 10.1021/jacs.7b02213.
Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function
Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC.
Immunity. 2016 Nov 15;45(5):975-987. doi: 10.1016/j.immuni.2016.10.011.
The Art of Basic Science Series
A side project purely for my own amusement.
Subunit-Specific Labeling of Ubiquitin Chains by Using Sortase: Insights into the Selectivity of Deubiquitinases
Crowe SO, Pham GH, Ziegler JC, Deol KK, Guenette RG, Ge Y, Strieter ER.
Chembiochem. 2016 Aug 17;17(16):1525-31.
Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling
Abo M, Li C, Weerapana E.
Mol Pharm. 2018 Mar 5;15(3):743-749.
Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis
Alexander J. Wagner, Dmitry Yu. Zabarev, Alan Aspuru-Gusik, and Donna G. Blackmond.
ACS Cent. Sci., 2017, 3 (4), pp 322–328.
Extensive horizontal gene transfer in cheese-associated bacteria